Yes you can. But you have to know what protocol is used (I2C, microwire, SPI), so that you can write communication routines. What kind of LCD do you have? Is it an LCD module or only numeric display with driver or is it a graphics display? So figure out:
1. what serial interface and protocol is used
2. what commands are used to drive the display driver
3. how to define a character if non character display is used
4. how to write a character to the display and how to erase it

Those are also the steps you should take to make your LCD alive.